The 3-dimensional random walk with applications to overstretched DNA and the protein titin
arXiv:0803.0878 · doi:10.1016/j.physa.2008.09.014
Abstract
We study the three-dimensional persistent random walk with drift. Then we develop a thermodynamic model that is based on this random walk without assuming the Boltzmann-Gibbs form for the equilibrium distribution. The simplicity of the model allows us to perform all calculations in closed form. We show that, despite its simplicity, the model can be used to describe different polymer stretching experiments. We study the reversible overstretching transition of DNA and the static force-extension relation of the protein titin.
9 pages, 10 figures
References in corpus (8)
- Stretching Single Domain Proteins: Phase Diagram and Kinetics of Force-Induced Unfolding
- Stretching of a polymer below the Theta point
- Force induced conformational transition in a system of interacting stiff polymer: Application to unfolding
- The bend stiffness of S-DNA
- A one-dimensional model for theoretical analysis of single molecule experiments
- Transition records of stationary Markov chains
- A two-parameter random walk with approximate exponential probability distribution
- Residual entropy in a model for the unfolding of single polymer chains