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- Rice UniversityUS4 papers
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- Hefei National Center for Physical Sciences at NanoscaleCN1 paper
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physics.bio-ph2026
Shape-Independent Fluidity in Epithelial Cell Monolayers
Pradip K. Bera, Anh Q. Nguyen, Molly McCord +2
Tissue fluidity regulates biological processes such as embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effective…
physics.bio-ph2026★ 23 cited
Leak Proof PDBBind: A Reorganized Dataset of Protein-Ligand Complexes for More Generalizable Binding Affinity Prediction
Jie Li, Xingyi Guan, Oufan Zhang +4
The majority of machine learning scoring functions used in drug discovery for predicting protein-ligand binding poses and affinities have been trained on the PDBBind dataset. Howev…
physics.bio-ph2025
Topology of the simplest gene switch
Aleksandra Nelson, Peter Wolynes, Evelyn Tang
Complex gene regulatory networks often display emergent simple behavior. Sometimes this simplicity can be traced to a nearly equivalent energy landscape, but not always. Here, we s…