139 citations
- Stanford UniversityUS2 papers
- Texas A&M UniversityUS2 papers
- University of WarwickGB2 papers
- Artificial Intelligence in Medicine (Canada)CA1 paper
- Assistance Publique – Hôpitaux de ParisFR1 paper
- Auburn UniversityUS1 paper
- Bayer (Switzerland)CH1 paper
- BOKU UniversityAT1 paper
- Centre for Biomedical Network Research on Rare DiseasesES1 paper
- Centro de Investigacion Principe FelipeES1 paper
- Columbia UniversityUS1 paper
- Cornell UniversityUS1 paper
7 papers
Designing binary mixtures of colloidal particles with simple interactions that assemble complex crystals
Beth Hsiao-Yen Wei, C. Levi Petix, Qizan Chen +2
Computational methods for designing interactions between colloidal particles that induce self-assembly have received much attention for their promise to discover tailored materials…
In silico clinical trials in drug development: a systematic review
Bohua Chen, Lucia Chantal Schneider, Christian Röver +15
In the context of clinical research, computational models have received increasing attention over the past decades. In this systematic review, we aimed to provide an overview of th…
Sequential Experimental Design for Optimal Structural Intervention in Gene Regulatory Networks Based on the Mean Objective Cost of Uncertainty
Mahdi Imani, Roozbeh Dehghannasiri, Ulisses M. Braga-Neto +1
Scientists are attempting to use models of ever increasing complexity, especially in medicine, where gene-based diseases such as cancer require better modeling of cell regulation.…
Interpreting the dependence of mutation rates on age and time
Ziyue Gao, Minyoung J. Wyman, Guy Sella +1
Mutations can arise from the chance misincorporation of nucleotides during DNA replication or from DNA lesions that are not repaired correctly. We introduce a model that relates th…
Assessing Technical Performance in Differential Gene Expression Experiments with External Spike-in RNA Control Ratio Mixtures
Sarah A. Munro, Steve P. Lund, P. Scott Pine +30
There is a critical need for standard approaches to assess, report, and compare the technical performance of genome-scale differential gene expression experiments. We assess techni…
Towards Structural Classification of Proteins based on Contact Map Overlap
Rumen Andonov, Nicola Yanev, Noël Malod-Dognin
A multitude of measures have been proposed to quantify the similarity between protein 3-D structure. Among these measures, contact map overlap (CMO) maximization deserved sustained…