85 citations
- Centre National de la Recherche ScientifiqueFR7 papers
- InsermFR7 papers
- Laboratoire Interdisciplinaire de PhysiqueFR4 papers
- Université Grenoble AlpesFR3 papers
- Université Joseph FourierFR3 papers
- École Normale Supérieure de LyonFR2 papers
- Laboratoire de Biologie et Modélisation de la CelluleFR2 papers
- Laboratoire de Physique de l'ENS de LyonFR2 papers
- Université de LyonFR2 papers
- CEA GrenobleFR1 paper
- Center for Integrated Protein Science MunichDE1 paper
- Center for NanoScienceDE1 paper
7 papers
Mechanical behavior of multi-cellular spheroids under osmotic compression
Monika Dolega, Giuseppe Zurlo, Magali Le Goff +5
The internal and external mechanical environment plays an important role in tumorogenesis. As a proxy of an avascular early state tumor, we use multicellular spheroids, a composite…
QuanTI-FRET: a framework for quantitative FRET measurements in living cells
Alexis Coullomb, Cecile M. Bidan, Chen Qian +5
Foerster Resonance Energy Transfer (FRET) allows for the visualization of nanometer-scale distances and distance changes. This sensitivity is regularly achieved in single-molecule…
Kinky DNA in solution: Small angle scattering study of a nucleosome positioning sequence
Torben Schindler, Adrián González, Ramachandran Boopathi +10
DNA is a flexible molecule, but the degree of its flexibility is subject to debate. The commonly-accepted persistence length of Å is inconsistent with recent stu…
Correction of cell-induced optical aberrations in a fluorescence fluctuation microscope
Charles-Edouard Leroux, Alexei Grichine, Irène Wang +1
We describe the effect of optical aberrations on fluorescence fluctuations microscopy (FFM), when focusing through a single living cell. FFM measurements are performed in an aqueou…
From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism
Christian Villiers, Mireille Chevallet, Hélène Diemer +5
Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatib…
The dynamics of individual nucleosomes controls the chromatin condensation pathway: direct AFM visualization of variant chromatin
Fabien Montel, Hervé Menoni, Martin Castelnovo +4
Chromatin organization and dynamics is studied in this work at scales ranging from single nucleosome to nucleosomal array by using a unique combination of biochemical assays, singl…