33 citations
6 papers
Diagonal free homonuclear 2D correlation using heteronuclei
Bikash Baishya
Homonuclear correlation spectroscopy has played a crucial role in elucidating structure of molecules in solution. In all kinds of homonuclear correlation, the most intense peaks ap…
Pseudo 5D HN(C)N Experiment to Facilitate the Assignment of Backbone Resonances in Proteins Exhibiting High Backbone Shift Degeneracy
Dinesh Kumar, Nisha Raikwal, Vaibhav Kumar Shukla +3
Assignment of protein backbone resonances is most routinely carried out using triple resonance three dimensional NMR experiments involving amide 1H and 15N resonances. However for…
Metabolite Characterization in Peritoneal Dialysis Effluent Using High-resolution 1H and 1H-13C NMR Spectroscopy
Anupam Guleria, Nitin Kumar Bajpai, Atul Rawat +3
Metabolite analysis of peritoneal dialysis (PD) effluent may provide information regarding onset and progression of complications associated with prolonged PD therapy. In this cont…
Reduced Dimensionality tailored HN(C)N Pulse Sequences for Efficient Backbone Resonance Assignment of Proteins through Rapid Identification of Sequential HSQC peaks
Dinesh Kumar
Two novel reduced dimensionality (RD) experiments -(4,3)D-hNCOcaNH and (4,3)D-hNcoCANH- have been presented here to facilitate the backbone resonance assignment of proteins both in…
Perfect Echo HMQC: Sensitivity and Resolution Enhancement by Broadband Homonuclear Decoupling
Bikash Baishya, C. L Khetrapala, Krishna Kishor Dey
Homonuclear 1H-1H J-modulation leads to J-multiplets in F1 dimension of 2D 1H-13C HMQC spectra. This hampers unambiguous signal assignment for overcrowded 13C spectra. Broadband ho…
Reduced Dimensionality (4,3)D-hnCOCANH Experiment: An Efficient Backbone Assignment tool for NMR studies of Proteins
Dinesh Kumar
Sequence specific resonance assignment and secondary structure determination of proteins form the basis for variety of structural and functional proteomics studies by NMR. In this…