output
20082025
most citedFrom secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism

85 citations

Showing q-bio.GNShow all

5 papers · 1 filter

q-bio.GN2014★ 21 cited

The proteomic to biology inference, a frequently overlooked concern in the interpretation of proteomic data: A plea for functional validation

Thierry Rabilloud, Pierre Lescuyer

Proteomics will celebrate its 20th year in 2014. In this relatively short period of time, it has invaded most areas of biology and its use will probably continue to spread in the f…

q-bio.GN2011★ 7 cited

Effects of nanoparticles on murine macrophages

Mireille Chevallet, Catherine Aude-Garcia, Cécile Lelong +8

Metallic nanoparticles are more and more widely used in an increasing number of applications. Consequently, they are more and more present in the environment, and the risk that the…

q-bio.GN2009★ 84 cited

Power and limitations of electrophoretic separations in proteomics strategies

Thierry Rabilloud, Ali R Vaezzadeh, Noelle Potier +3

Proteomics can be defined as the large-scale analysis of proteins. Due to the complexity of biological systems, it is required to concatenate various separation techniques prior to…

q-bio.GN2009★ 85 cited

From secretome analysis to immunology: chitosan induces major alterations in the activation of dendritic cells via a TLR4-dependent mechanism

Christian Villiers, Mireille Chevallet, Hélène Diemer +5

Dendritic cells are known to be activated by a wide range of microbial products, leading to cytokine production and increased levels of membrane markers such as major histocompatib…

q-bio.GN2008★ 12 cited

Mitochondrial proteomics: analysis of a whole mitochondrial extract with two-dimensional electrophoresis

Thierry Rabilloud

Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from…