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45 papers · 1 filter
Membrane tubes with active pumping: water transport, vacuole formation and osmoregulation
Sami C. Al-Izzi, Matthew S. Turner, Pierre Sens
The need for organisms to regulate their volume and osmolarity when surrounded by freshwater is a basic physical challenge for many bacteria, protists and algae. Taking inspiration…
Uncovering multiscale structure in the variability of larval zebrafish navigation
Gautam Sridhar, Massimo Vergassola, Joao C. Marques +3
Animals chain movements into long-lived motor strategies, exhibiting variability across scales that reflects the interplay between internal states and environmental cues. To reveal…
Cytoplasmic Viscosity is a Potential Biomarker for Metastatic Breast Cancer Cells
Marie Dessard, Jean-Baptiste Manneville, Jean-François Berret
Cellular microrheology has shown that cancer cells with high metastatic potential are softer compared to non-tumorigenic normal cells. These findings rely on measuring the apparent…
AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors
Léna Carmès, Guillaume Bort, François Lux +16
Comparison of click chemistry and sortagging grafting strategies for functionalizing AGuIX nanoparticles with nanobodies to develop a tri-functional technology combining MRI imagin…
Specialized pro-resolving mediator Resolvin E1 corrects the altered cystic fibrosis nasal epithelium cilia beating dynamics
Valerie Urbach, Maëlle Briottet, Khadeeja Sy +6
In cystic fibrosis (CF), impaired mucociliary clearance leads to chronic infection and inflammation. However, cilia beating features in a CF altered environment, consisting of dehy…
Native Mass Spectrometry and Nucleic Acid G-Quadruplex Biophysics: Advancing Hand in Hand
Valérie Gabelica
While studying nucleic acids to reveal the weak interactions responsible for their three-dimensional structure and for their interactions with drugs, we also contributed to the fie…