output
20182025
most citedDeep learning-based transformation of the H&E stain into special stains

323 citations

8 papers

eess.IV2025

Learn2Reg 2024: New Benchmark Datasets Driving Progress on New Challenges

Lasse Hansen, Wiebke Heyer, Christoph Großbröhmer +51

Medical image registration is critical for clinical applications, and fair benchmarking of different methods is essential for monitoring ongoing progress in the field. To date, the…

eess.IV2024

Digital Volumetric Biopsy Cores Improve Gleason Grading of Prostate Cancer Using Deep Learning

Ekaterina Redekop, Mara Pleasure, Zichen Wang +5

Prostate cancer (PCa) was the most frequently diagnosed cancer among American men in 2023. The histological grading of biopsies is essential for diagnosis, and various deep learnin…

eess.IV2023★ 8 cited

Ultrasound Image Enhancement using CycleGAN and Perceptual Loss

Shreeram Athreya, Ashwath Radhachandran, Vedrana Ivezić +3

Purpose: The objective of this work is to introduce an advanced framework designed to enhance ultrasound images, especially those captured by portable hand-held devices, which ofte…

eess.IV2023★ 6 cited

Clinically Relevant Latent Space Embedding of Cancer Histopathology Slides through Variational Autoencoder Based Image Compression

Mohammad Sadegh Nasr, Amir Hajighasemi, Paul Koomey +6

In this paper, we introduce a Variational Autoencoder (VAE) based training approach that can compress and decompress cancer pathology slides at a compression ratio of 1:512, which…

eess.IV2022★ 10 cited

A SSIM Guided cGAN Architecture For Clinically Driven Generative Image Synthesis of Multiplexed Spatial Proteomics Channels

Jillur Rahman Saurav, Mohammad Sadegh Nasr, Paul Koomey +7

Here we present a structural similarity index measure (SSIM) guided conditional Generative Adversarial Network (cGAN) that generatively performs image-to-image (i2i) synthesis to g…

physics.med-ph2021★ 15 cited

Tomographic phase and attenuation extraction for a sample composed of unknown materials using X-ray propagation-based phase-contrast imaging

Samantha J. Alloo, David M. Paganin, Kaye S. Morgan +9

Propagation-based phase-contrast X-ray imaging (PB-PCXI) generates image contrast by utilizing sample-imposed phase-shifts. This has proven useful when imaging weakly-attenuating s…

eess.IV2020★ 323 cited

Deep learning-based transformation of the H&E stain into special stains

Kevin de Haan, Yijie Zhang, Jonathan E. Zuckerman +11

Pathology is practiced by visual inspection of histochemically stained slides. Most commonly, the hematoxylin and eosin (H&E) stain is used in the diagnostic workflow and it is the…

cs.CV2018★ 9 cited

An Interpretable Deep Hierarchical Semantic Convolutional Neural Network for Lung Nodule Malignancy Classification

Shiwen Shen, Simon X. Han, Denise R. Aberle +2

While deep learning methods are increasingly being applied to tasks such as computer-aided diagnosis, these models are difficult to interpret, do not incorporate prior domain knowl…