output
20162024
most citedUltrasound-mediated Cavitation-enhanced extravasation of mesoporous silica nanoparticles for controlled-release drug delivery

117 citations

14 papers

cs.LG2024★ 21 cited

Classification of Radiologically Isolated Syndrome and Clinically Isolated Syndrome with Machine-Learning Techniques

V Mato-Abad, A Labiano-Fontcuberta, S Rodriguez-Yanez +9

Background and purpose: The unanticipated detection by magnetic resonance imaging (MRI) in the brain of asymptomatic subjects of white matter lesions suggestive of multiple scleros…

q-bio.TO2021★ 81 cited

Cerium (III) and (IV) containing mesoporous glasses/alginate beads for bone regeneration: bioactivity, biocompatibility and reactive oxygen species activity

E. Varini, S. Sanchez-Salcedo, G. Malavasi +3

A very small number of biomaterials investigated for bone regeneration was reported as able to prevent the oxidative stress. In this study beads based on alginate hydrogel and meso…

q-bio.TO2021★ 10 cited

Metabolomic response of osteosarcoma cells to nanographene oxide-mediated hyperthermia

Monica Cicuendez, Joana Flores, Helena Oliveira +4

Nanographene oxide (nGO)-mediated hyperthermia has been increasingly investigated as a localised, minimally invasive anticancer therapeutic approach. Near InfraRed (NIR) light irra…

q-bio.BM2021★ 61 cited

Osteostatin potentiates the bioactivity of mesoporous glass scaffolds containing Zn2+ ions in human mesenchymal stem cell cultures

C. Heras, S. Sanchez-Salcedo, D. Lozano +4

There is an urgent need of biosynthetic bone grafts with enhanced osteogenic capacity. In this study, we describe the design of hierarchical meso-macroporous 3D-scaffolds based on…

q-bio.QM2021★ 84 cited

Multifunctional antibiotic- and zinc-containing mesoporous bioactive glass scaffolds to fight bone infection

C. Heras, J. Jimenez Holguin, A. L. Doadrio +3

Bone regeneration is a clinical challenge that requires multiple approaches. Sometimes, it also includes the development of new osteogenic and antibacterial biomaterials to treat t…

q-bio.QM2021★ 42 cited

Development and evaluation of copper-containing mesoporous bioactive glasses for bone defects therapy

J Jimenez-Holguin, S Sanchez-Salcedo, M Vallet-Regi +1

Mesoporous bioactive glasses, MBG, are gaining increasing interest in the design of new biomaterials for bone defects treatment. An important research trend to enhance their biolog…

q-bio.TO2021★ 48 cited

Collagenase Nanocapsules: An Approach to Fibrosis Treatment

MR Villegas, A Baeza, A Usategui +3

Fibrosis is a common lesion in different pathologic diseases and is defined by the excessive accumulation of collagen. Different approaches have been used to treat different condit…

q-bio.TO2021★ 117 cited

Ultrasound-mediated Cavitation-enhanced extravasation of mesoporous silica nanoparticles for controlled-release drug delivery

JL Paris, C Mannris, M Cabanas +4

Mesoporous silica nanoparticles have been reported as suitable drug carriers, but their successful delivery to target tissues following systemic administration remains a challenge.…

q-bio.TO2021★ 32 cited

Suicide-Gene Transfection of Tumor-tropic Placental Stem Cells employing Ultrasound-Responsive Nanoparticles

Juan L. Paris, Paz de la Torre, M. Victoria Cabanas +3

A Trojan-horse strategy for cancer therapy employing tumor-tropic mesenchymal stem cells transfected with a non-viral nanovector is here presented. In this sense, ultrasound-respon…

q-bio.TO2021★ 92 cited

3D scaffold with effective multidrug sequential release against bacteria biofilm

Rafaela Garcia-Alvarez, Isabel Izquierdo-Barba, Maria Vallet-Regi

Bone infection is a feared complication following surgery or trauma that remains as an extremely difficult disease to deal with. So far, the outcome of therapy could be improved wi…

eess.IV2020★ 59 cited

Ensembles of Convolutional Neural Networks models for pediatric pneumonia diagnosis

Helena Liz, Manuel Sánchez-Montañés, Alfredo Tagarro +3

Pneumonia is a lung infection that causes 15% of childhood mortality, over 800,000 children under five every year, all over the world. This pathology is mainly caused by viruses or…

cond-mat.soft2020★ 15 cited

Moulding hydrodynamic 2D-crystals upon parametric Faraday waves in shear-functionalized water surfaces

Mikheil Kharbedia, Niccolò Caselli, Horacio López-Menéndez +2

Faraday waves (FWs), or surface waves oscillating at half of the natural frequency when a liquid is vertically vibrated, are archetypes of ordering transitions on liquid surfaces.…

cond-mat.soft2019★ 9 cited

Membrane stress and torque induced by Frank's nematic textures: A geometric perspective using surface-based constraints

J. A. Santiago, G. Chacón-Acosta, F. Monroy

An elastic membrane with embedded nematic molecules is considered as a model of anisotropic fluid membrane with internal ordering. By considering the geometric coupling between dir…

cs.HC2016★ 100 cited

Computer keyboard interaction as an indicator of early Parkinson's disease

L. Giancardo, A. Sánchez-Ferro, T. Arroyo-Gallego +7

Parkinson's disease (PD) is a slowly progressing neurodegenerative disease with early manifestation of motor signs. Objective measurements of motor signs are of vital importance fo…