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5 papers · 1 filter
Coffea-Casa: Building composable analysis facilities for the HL-LHC
Sam Albin, Garhan Attebury, Kenneth Bloom +4
The large data volumes expected from the High Luminosity LHC (HL-LHC) present challenges to existing paradigms and facilities for end-user data analysis. Modern cyberinfrastructure…
Community recommendations on cryoEM data archiving and validation
Gerard J. Kleywegt, Paul D. Adams, Sarah J. Butcher +44
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle anal…
Reproducible image-based profiling with Pycytominer
Erik Serrano, Srinivas Niranj Chandrasekaran, Dave Bunten +25
Advances in high-throughput microscopy have enabled the rapid acquisition of large numbers of high-content microscopy images. Whether by deep learning or classical algorithms, imag…
Current and future directions in network biology
Marinka Zitnik, Michelle M. Li, Aydin Wells +34
Network biology is an interdisciplinary field bridging computational and biological sciences that has proved pivotal in advancing the understanding of cellular functions and diseas…
A Text-guided Protein Design Framework
Shengchao Liu, Yanjing Li, Zhuoxinran Li +10
Current AI-assisted protein design mainly utilizes protein sequential and structural information. Meanwhile, there exists tremendous knowledge curated by humans in the text format…