output
20142025
most citedSubgroup-Based Adaptive (SUBA) Designs for Multi-Arm Biomarker Trials

42 citations

researchers with a paper here

Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.

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Showing 2017Show all

3 papers · 1 filter

stat.ME2017

AAA: Triple-adaptive Bayesian designs for the identification of optimal dose combinations in dual-agent dose-finding trials

Jiaying Lyu, Yuan Ji, Naiqing Zhao +1

We propose a flexible design for the identification of optimal dose combinations in dual-agent dose-finding clinical trials. The design is called AAA, standing for three adaptation…

stat.AP2017★ 1 cited

TreeClone: Reconstruction of Tumor Subclone Phylogeny Based on Mutation Pairs using Next Generation Sequencing Data

Tianjian Zhou, Subhajit Sengupta, Peter Mueller +1

We present TreeClone, a latent feature allocation model to reconstruct tumor subclones subject to phylogenetic evolution that mimics tumor evolution. Similar to most current method…

stat.AP2017★ 8 cited

PairClone: A Bayesian Subclone Caller Based on Mutation Pairs

Tianjian Zhou, Peter Mueller, Subhajit Sengupta +1

Tumor cell populations can be thought of as being composed of homogeneous cell subpopulations, with each subpopulation being characterized by overlapping sets of single nucleotide…