177 citations
- Assistance Publique – Hôpitaux de ParisFR5 papers
- Centre National de la Recherche ScientifiqueFR3 papers
- InsermFR3 papers
- Centre d'études et de recherche en informatique et communicationsFR2 papers
- Délégation Paris 7FR2 papers
- Sorbonne Paris CitéFR2 papers
- Université Paris CitéFR2 papers
- Amélioration Génétique et Adaptation des Plantes méditerranéennes et tropicalesFR1 paper
- Bicêtre HospitalFR1 paper
- Cambridge University PressGB1 paper
- Centre de Coopération Internationale en Recherche Agronomique pour le DéveloppementFR1 paper
- Centre de Recherche en Biologie cellulaire de MontpellierFR1 paper
7 papers
Clinical research and methodology What usage and what hierarchical order for secondary endpoints?
Silvy Laporte, Marine Diviné, Danièle Girault +12
In a randomised clinical trial, when the result of the primary endpoint shows a significant benefit, the secondary endpoints are scrutinised to identify additional effects of the t…
Evaluation of the mitotic score of invasive breast carcinomas on digital slide: development and contribution of a mitosis detection algorithm
Loris Guichard, Clara Simmat, Margot Dupeux +6
Introduction: Nottingham grading system is a major prognostic factor for invasive breast carcinoma (IBC). Its determination requires the evaluation of the mitotic score (MS) which…
Clustering with missing data: which imputation model for which cluster analysis method?
Vincent Audigier, Ndèye Niang, Matthieu Resche-Rigon
Multiple imputation (MI) is a popular method for dealing with missing values. One main advantage of MI is to separate the imputation phase and the analysis one. However, both are r…
Combining Bayesian and Deep Learning Methods for the Delineation of the Fan in Ultrasound Images
Hind Dadoun, Hervé Delingette, Anne-Laure Rousseau +2
Ultrasound (US) images usually contain identifying information outside the ultrasound fan area and manual annotations placed by the sonographers during exams. For those images to b…
Analyzing huge pathology images with open source software
Christophe Deroulers, David Ameisen, Mathilde Badoual +3
Backgr: Digital pathology images are increasingly used both for diagnosis and research, because slide scanners are nowadays broadly available and because the quantitative study of…
Multiple imputation for multilevel data with continuous and binary variables
Vincent Audigier, Ian R. White, Shahab Jolani +5
We present and compare multiple imputation methods for multilevel continuous and binary data where variables are systematically and sporadically missing. The methods are compared f…