50 citations
- Statistical Research (United States)US25 papers
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7 papers · 1 filter
Degrees-of-Freedom Approximations for Conditional-Mean Inference in Random-Lot Stability Analysis
Andrew T. Karl, Heath Rushing, Richard K. Burdick +1
Linear mixed models are widely used for pharmaceutical stability trending when sufficient lots are available. Expiry support is often based on whether lot-specific conditional-mean…
A Practical Approach to Proper Inference with Linked Data
Andee Kaplan, Brenda Betancourt, Rebecca C. Steorts
Entity resolution (ER), comprising record linkage and de-duplication, is the process of merging noisy databases in the absence of unique identifiers to remove duplicate entities. O…
Conditional and marginal relative risk parameters for a class of recursive regression graph models
Monia Lupparelli
In linear regression modelling the distortion of effects after marginalizing over variables of the conditioning set has been widely studied in several contexts. For Gaussian variab…
Model Choice and Diagnostics for Linear Mixed-Effects Models Using Statistics on Street Corners
Adam Loy, Heike Hofmann, Dianne Cook
The complexity of linear mixed-effects (LME) models means that traditional diagnostics are rendered less effective. This is due to a breakdown of asymptotic results, boundary issue…
High Dimensional Forecasting via Interpretable Vector Autoregression
William B. Nicholson, Ines Wilms, Jacob Bien +1
Vector autoregression (VAR) is a fundamental tool for modeling multivariate time series. However, as the number of component series is increased, the VAR model becomes overparamete…
Meta-Analysis of Gene Level Association Tests
Dajiang J. Liu, Gina M. Peloso, Xiaowei Zhan +18
The vast majority of connections between complex disease and common genetic variants were identified through meta-analysis, a powerful approach that enables large samples sizes whi…