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20152025
most citedPrediction, dynamics, and visualization of antigenic phenotypes of seasonal influenza viruses

265 citations

Showing q-bio.MNShow all

5 papers · 1 filter

q-bio.MN2019★ 8 cited

Extraction and integration of genetic networks from short-profile omic datasets

Jacopo Iacovacci, Alina Peluso, Timothy Ebbels +2

Mass-spectrometry technologies are widely used in the fields of ionomics and metabolomics to simultaneously profile at the genome scale intracellular concentrations of e.g. amino a…

q-bio.MN2017★ 35 cited

Memory functions reveal structural properties of gene regulatory networks

Edgar Herrera-Delgado, Ruben Perez-Carrasco, James Briscoe +1

Gene regulatory networks (GRNs) control cellular function and decision making during tissue development and homeostasis. Mathematical tools based on dynamical systems theory are of…

q-bio.MN2016

On the role of extrinsic noise in microRNA-mediated bimodal gene expression

Marco Del Giudice, Stefano Bo, Silvia Grigolon +1

Several studies highlighted the relevance of extrinsic noise in shaping cell decision making and differentiation in molecular networks. Experimental evidences of phenotypic differe…

q-bio.MN2016★ 96 cited

Intrinsic noise profoundly alters the dynamics and steady state of morphogen-controlled bistable genetic switches

Ruben Perez-Carrasco, Pilar Guerrero, James Briscoe +1

During tissue development, patterns of gene expression determine the spatial arrangement of cell types. In many cases, gradients of secreted signaling molecules - morphogens - guid…

q-bio.MN2016★ 14 cited

Noise Processing by MicroRNA-Mediated Circuits: the Incoherent Feed-Forward Loop, Revisited

Silvia Grigolon, Francesca Di Patti, Andrea De Martino +1

The intrinsic stochasticity of gene expression is usually mitigated in higher eukaryotes by post-transcriptional regulation channels that stabilise the output layer, most notably p…