6 citations
- University of PennsylvaniaUS2 papers
- Columbia UniversityUS1 paper
- Columbia University Irving Medical CenterUS1 paper
- InsermFR1 paper
- Lund UniversitySE1 paper
- Penn Center for AIDS ResearchUS1 paper
- Seoul National UniversityKR1 paper
- University of FloridaUS1 paper
- University of TehranIR1 paper
- University of Wisconsin–MilwaukeeUS1 paper
35 papers
Cross-scale spatially-aware generative modeling of transcriptomic programs underlying neurodegenerative brain organization
Krishnakumar Vaithianathan
Neurodegenerative disorders such as Alzheimer's disease exhibit highly organized patterns of regional brain vulnerability, yet the biological mechanisms underlying this spatial sel…
Understanding Sources of Demographic Predictability in Brain MRI via Disentangling Anatomy and Contrast
Mehmet Yigit Avci, Akshit Achara, Andrew King +1
Demographic attributes can be predicted from medical images, raising concerns about bias in clinical AI systems. In X-ray imaging, acquisition characteristics have been shown to co…
Improving operating characteristics of clinical trials by augmenting control arm using propensity score-weighted borrowing-by-parts power prior
Apu Chandra Das, Sakib Salam, Aninda Roy +3
Borrowing external data can improve estimation efficiency but may introduce bias when populations differ in covariate distributions or outcome variability. A proper balance needs t…
MethConvTransformer: A Deep Learning Framework for Cross-Tissue Alzheimer's Disease Detection
Gang Qu, Guanghao Li, Zhongming Zhao
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by progressive cognitive decline and widespread epigenetic dysregulation in the brain. DNA met…
R-GenIMA: Integrating Neuroimaging and Genetics with Interpretable Multimodal AI for Alzheimer's Disease Progression
Kun Zhao, Siyuan Dai, Yingying Zhang +9
Early detection of Alzheimer's disease (AD) requires models capable of integrating macro-scale neuroanatomical alterations with micro-scale genetic susceptibility, yet existing mul…
Alzheimer's Clinical Research Data via R Packages: the alzverse
Michael C. Donohue, Kedir Hussen, Oliver Langford +3
Sharing clinical research data is essential for advancing research in Alzheimer's disease (AD) and other therapeutic areas. However, challenges in data accessibility, standardizati…