5 citations
2 papers
stat.ME2024★ 5 cited
ROMI: A Randomized Two-Stage Basket Trial Design to Optimize Doses for Multiple Indications
Shuqi Wang, Peter F. Thall, Kentaro Takeda +1
Optimizing doses for multiple indications is challenging. The pooled approach of finding a single optimal biological dose (OBD) for all indications ignores that dose-response or do…
stat.AP2015
Flexible combination of multiple diagnostic biomarkers to improve diagnostic accuracy
Tu Xu, Yixin Fang, Alan Rong +1
In medical research, it is common to collect information of multiple continuous biomarkers to improve the accuracy of diagnostic tests. Combining the measurements of these biomarke…