output
20132024
most citedAncient human genomes suggest three ancestral populations for present-day Europeans

1.5k citations

10 papers

physics.med-ph2024★ 6 cited

ezyMRI: How to build an MRI machine from scratch -- Experience from a four-day hackathon

Shaoying Huang, José Miguel Algarín, Joseba Alonso +25

Nuclear magnetic resonance instruments are becoming available to the do-it-yourself community. The challenges encountered in the endeavor to build a magnetic resonance imaging inst…

physics.ins-det2023★ 1 cited

Miniaturized 2D Scanning Microscopy with a Single 1D Actuation for Multi-Beam Optical Coherence Tomography

Rachel Yixuan Tan, Rachel Chi Kei Chan, Whitney Jia Ying Loh +1

Miniaturized optical imaging systems typically utilize 2-dimensional (2D) actuators to acquire images over a 2D field of view (FOV). Piezoelectric tubes are most compact, but usual…

cs.NE2021★ 6 cited

A nonlinear hidden layer enables actor-critic agents to learn multiple paired association navigation

M Ganesh Kumar, Cheston Tan, Camilo Libedinsky +2

Navigation to multiple cued reward locations has been increasingly used to study rodent learning. Though deep reinforcement learning agents have been shown to be able to learn the…

q-bio.BM2021★ 1 cited

Growth and site-specific organization of micron-scale biomolecular devices on living mammalian cells

Sisi Jia, Siew Cheng Phua, Yuta Nihongaki +7

Mesoscale molecular assemblies on the cell surface, such as cilia and filopodia, integrate information, control transport and amplify signals. Synthetic devices mimicking these str…

q-bio.MN2018

Transcriptional Activation of Elephant Shark Mineralocorticoid Receptor by Corticosteroids, Progesterone and Spironolactone

Yoshinao Katsu, Satomi Kohno, Kaori Oka +7

We report the analysis of activation by corticosteroids and progesterone of full-length mineralocorticoid receptor (MR) from elephant shark, a cartilaginous fish belonging to the o…

cs.CV2015★ 2 cited

Mouse Pose Estimation From Depth Images

Ashwin Nanjappa, Li Cheng, Wei Gao +3

We focus on the challenging problem of efficient mouse 3D pose estimation based on static images, and especially single depth images. We introduce an approach to discriminatively t…

q-bio.BM2015

DNA cyclization and looping in the wormlike limit: normal modes and the validity of the harmonic approximation

Stefan M. Giovan, Andreas Hanke, Stephen D. Levene

For much of the last three decades Monte Carlo-simulation methods have been the standard approach for accurately calculating the cyclization probability, , or J factor, for DNA…

q-bio.MN2015★ 9 cited

Aggregation-fragmentation model of robust concentration gradient formation

Timothy E Saunders

Concentration gradients of signaling molecules are essential for patterning during development and they have been observed in both unicellular and multicellular systems. In subcell…

q-bio.PE2013★ 1.5k cited

Ancient human genomes suggest three ancestral populations for present-day Europeans

Iosif Lazaridis, Nick Patterson, Alissa Mittnik +117

We sequenced genomes from a 7,000 year old early farmer from Stuttgart in Germany, an 8,000 year old hunter-gatherer from Luxembourg, and seven 8,000 year old hun…

q-bio.GN2013

The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation

Qi Zhou, Christopher E. Ellison, Vera B. Kaiser +3

Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertranscribed due to dosage compensat…