14 citations
- Centre National de la Recherche ScientifiqueFR6 papers
- InsermFR6 papers
- Lyon 1 UniversitéFR2 papers
- Université de BordeauxFR2 papers
- Université Paris CitéFR2 papers
- Université Paris Sciences et LettresFR2 papers
- AgroParisTechFR1 paper
- Biologie cellulaire et CancerFR1 paper
- Biologie cellulaire physiologique et pathologiqueFR1 paper
- Bordeaux Population HealthFR1 paper
- Centre de Recherche des CordeliersFR1 paper
- Centre de Recherche en Cancérologie de LyonFR1 paper
8 papers
Reduction Techniques for Survival Analysis
Johannes Piller, Léa Orsini, Simon Wiegrebe +6
In this work, we discuss what we refer to as reduction techniques for survival analysis, that is, techniques that "reduce" a survival task to a more common regression or classifica…
Estimating Disease-Free Life Expectancy based on Clinical Data from the French Hospital Discharge Database
Oleksandr Sorochynskyi, Quentin Guibert, Frédéric Planchet +1
The development of health indicators to measure healthy life expectancy (HLE) is an active field of research aimed at summarizing the health of a population. Although many health i…
Deciphering circulating tumor cells binding in a microfluidic system thanks to a parameterized mathematical model
Giorgia Ciavolella, Julien Granet, Jacky Goetz +3
The spread of metastases is a crucial process in which some questions remain unanswered. In this work, we focus on tumor cells circulating in the bloodstream, the so-called Circula…
Models of Vimentin Organization Under Actin-Driven Transport
Youngmin Park, Cécile Leduc, Sandrine Etienne-Manneville +1
Intermediate filaments form an essential structural network, spread throughout the cytoplasm and play a key role in cell mechanics, intracellular organization and molecular signali…
Penalized Poisson model for network meta-analysis of individual patient time-to-event data
Edouard Ollier, Pierre Blanchard, Gwénaël Le Teuff +1
Network meta-analysis (NMA) allows the combination of direct and indirect evidence from a set of randomized clinical trials. Performing NMA using individual patient data (IPD) is c…
Knockdown of human AMPK using the CRISPR-Cas9 genome-editing system
Adrien Grenier, Pierre Sujobert, Séverine Olivier +5
AMP activated protein kinase (AMPK) is a critical energy sensor, regulating signaling networks involved in pathology including metabolic diseases and cancer. This increasingly reco…