output
20132024
most citedAncient human genomes suggest three ancestral populations for present-day Europeans

1.5k citations

9 papers

cs.RO2024★ 5 cited

Invariant neuromorphic representations of tactile stimuli improve robustness of a real-time texture classification system

Mark M. Iskarous, Zan Chaudhry, Fangjie Li +7

Humans have an exquisite sense of touch which robotic and prosthetic systems aim to recreate. We developed algorithms to create neuron-like (neuromorphic) spiking representations o…

cs.LO2022★ 2 cited

VWSIM: A Circuit Simulator

Warren A. Hunt, Vivek Ramanathan, J Strother Moore

VWSIM is a circuit simulator for rapid, single-flux, quantum (RSFQ) circuits. The simulator is designed to model and simulate primitive-circuit devices such as capacitors, inductor…

stat.AP2020

A Bias Correction Method in Meta-analysis of Randomized Clinical Trials with no Adjustments for Zero-inflated Outcomes

Zhengyang Zhou, Minge Xie, David Huh +1

Many clinical endpoint measures, such as the number of standard drinks consumed per week or the number of days that patients stayed in the hospital, are count data with excessive z…

stat.ME2018★ 13 cited

Generalized Similarity U: A Non-parametric Test of Association Based on Similarity

Changshuai Wei, Qing Lu

Second generation sequencing technologies are being increasingly used for genetic association studies, where the main research interest is to identify sets of genetic variants that…

q-bio.QM2017★ 24 cited

Protection of hamsters from mortality by reducing fecal moxifloxacin concentration with DAV131A in a model of moxifloxacin-induced Clostridium difficile colitis

Charles Burdet, Sakina Sayah-Jeanne, Thu Thuy Nguyen +7

BackgroundLowering the gut exposure to antibiotics during treatments can prevent microbiota disruption. We evaluated the effect of an activated charcoal-based adsorbent, DAV131A, o…

stat.ME2015★ 11 cited

A Weighted U Statistic for Genetic Association Analyses of Sequencing Data

Changshuai Wei, Ming Li, Zihuai He +3

With advancements in next generation sequencing technology, a massive amount of sequencing data are generated, offering a great opportunity to comprehensively investigate the role…

q-bio.QM2015★ 8 cited

GWGGI: software for genome-wide gene-gene interaction analysis

Changshuai Wei, Qing Lu

Background: While the importance of gene-gene interactions in human diseases has been well recognized, identifying them has been a great challenge, especially through association s…

stat.ME2015★ 7 cited

A weighted U statistic for association analysis considering genetic heterogeneity

Changshuai Wei, Robert C. Elston, Qing Lu

Converging evidence suggests that common complex diseases with the same or similar clinical manifestations could have different underlying genetic etiologies. While current researc…

q-bio.PE2013★ 1.5k cited

Ancient human genomes suggest three ancestral populations for present-day Europeans

Iosif Lazaridis, Nick Patterson, Alissa Mittnik +117

We sequenced genomes from a 7,000 year old early farmer from Stuttgart in Germany, an 8,000 year old hunter-gatherer from Luxembourg, and seven 8,000 year old hun…