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q-bio.PE2007★ 188 cited
The traveling wave approach to asexual evolution: Muller's ratchet and speed of adaptation
Igor M. Rouzine, Eric Brunet, Claus O. Wilke
We use traveling-wave theory to derive expressions for the rate of accumulation of deleterious mutations under Muller's ratchet and the speed of adaptation under positive selection…
q-bio.PE2007
The stochastic edge in adaptive evolution
Eric Brunet, Igor M. Rouzine, Claus O. Wilke
In a recent article, Desai and Fisher (2007) proposed that the speed of adaptation in an asexual population is determined by the dynamics of the stochastic edge of the population,…