28 citations
2 papers
stat.AP2014
Leveraging local identity-by-descent increases the power of case/control GWAS with related individuals
Joshua N. Sampson, Bill Wheeler, Peng Li +1
Large case/control Genome-Wide Association Studies (GWAS) often include groups of related individuals with known relationships. When testing for associations at a given locus, curr…
stat.ME2010★ 28 cited
On Combining Data From Genome-Wide Association Studies to Discover Disease-Associated SNPs
Ruth M. Pfeiffer, Mitchell H. Gail, David Pee
Combining data from several case-control genome-wide association (GWA) studies can yield greater efficiency for detecting associations of disease with single nucleotide polymorphis…