Publications (23)
Large Language Models for Manufacturing
Yiwei Li, Huaqin Zhao, Hanqi Jiang +21
The rapid advances in Large Language Models (LLMs) have the potential to transform manufacturing industry, offering new opportunities to optimize processes, improve efficiency, and…
Vibr-eau: Emulating Fluid Behavior in Vessel Handling through Vibrotactile Actuators
Frank Wencheng Liu, Ryan Wirjadi, Yanjun Lyu +4
Existing methods of haptic feedback for virtual fluids are challenging to scale, lack durability for long-term rough use, and fail to fully capture the expressive haptic qualities…
Classification of Mild Cognitive Impairment Based on Dynamic Functional Connectivity Using Spatio-Temporal Transformer
Jing Zhang, Yanjun Lyu, Xiaowei Yu +7
Dynamic functional connectivity (dFC) using resting-state functional magnetic resonance imaging (rs-fMRI) is an advanced technique for capturing the dynamic changes of neural activ…
Large Language Models for Bioinformatics
Wei Ruan, Yanjun Lyu, Jing Zhang +52
With the rapid advancements in large language model (LLM) technology and the emergence of bioinformatics-specific language models (BioLMs), there is a growing need for a comprehens…
Brain-Adapter: Enhancing Neurological Disorder Analysis with Adapter-Tuning Multimodal Large Language Models
Jing Zhang, Xiaowei Yu, Yanjun Lyu +7
Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to in…
Holistic Evaluation of GPT-4V for Biomedical Imaging
Zhengliang Liu, Hanqi Jiang, Tianyang Zhong +47
In this paper, we present a large-scale evaluation probing GPT-4V's capabilities and limitations for biomedical image analysis. GPT-4V represents a breakthrough in artificial gener…
Gyri vs. Sulci: Disentangling Brain Core-Periphery Functional Networks via Twin-Transformer
Xiaowei Yu, Lu Zhang, Haixing Dai +5
The human cerebral cortex is highly convoluted into convex gyri and concave sulci. It has been demonstrated that gyri and sulci are significantly different in their anatomy, connec…
Disentangling Spatial-Temporal Functional Brain Networks via Twin-Transformers
Xiaowei Yu, Lu Zhang, Lin Zhao +3
How to identify and characterize functional brain networks (BN) is fundamental to gain system-level insights into the mechanisms of brain organizational architecture. Current funct…
GyralNet Subnetwork Partitioning via Differentiable Spectral Modularity Optimization
Yan Zhuang, Minheng Chen, Chao Cao +7
Understanding the structural and functional organization of the human brain requires a detailed examination of cortical folding patterns, among which the three-hinge gyrus (3HG) ha…
Evaluation of OpenAI o1: Opportunities and Challenges of AGI
Tianyang Zhong, Zhengliang Liu, Yi Pan +73
This comprehensive study evaluates the performance of OpenAI's o1-preview large language model across a diverse array of complex reasoning tasks, spanning multiple domains, includi…
Core-Periphery Principle Guided Redesign of Self-Attention in Transformers
Xiaowei Yu, Lu Zhang, Haixing Dai +6
Designing more efficient, reliable, and explainable neural network architectures is critical to studies that are based on artificial intelligence (AI) techniques. Previous studies,…
Representing Brain Anatomical Regularity and Variability by Few-Shot Embedding
Lu Zhang, Xiaowei Yu, Yanjun Lyu +7
Effective representation of brain anatomical architecture is fundamental in understanding brain regularity and variability. Despite numerous efforts, it is still difficult to infer…
Vibe Medicine: Redefining Biomedical Research Through Human-AI Co-Work
Zihao Wu, Steven Xu, Bowen Chen +8
With the emergence of large language models (LLMs) and AI agent frameworks, the human-AI co-work paradigm known as Vibe Coding is changing how people code, making it more accessibl…
Bridging Brain Connectomes and Clinical Reports for Early Alzheimer's Disease Diagnosis
Jing Zhang, Xiaowei Yu, Minheng Chen +8
Integrating brain imaging data with clinical reports offers a valuable opportunity to leverage complementary multimodal information for more effective and timely diagnosis in pract…
Domain-Adaptive Diagnosis of Lewy Body Disease with Transferability Aware Transformer
Xiaowei Yu, Jing Zhang, Tong Chen +8
Lewy Body Disease (LBD) is a common yet understudied form of dementia that imposes a significant burden on public health. It shares clinical similarities with Alzheimer's disease (…
Core-Periphery Principle Guided State Space Model for Functional Connectome Classification
Minheng Chen, Xiaowei Yu, Jing Zhang +7
Understanding the organization of human brain networks has become a central focus in neuroscience, particularly in the study of functional connectivity, which plays a crucial role…
BrainNet-MoE: Brain-Inspired Mixture-of-Experts Learning for Neurological Disease Identification
Jing Zhang, Xiaowei Yu, Tong Chen +8
The Lewy body dementia (LBD) is the second most common neurodegenerative dementia after Alzheimer's disease (AD). Early differentiation between AD and LBD is crucial because they r…
GP-GPT: Large Language Model for Gene-Phenotype Mapping
Yanjun Lyu, Zihao Wu, Lu Zhang +11
Pre-trained large language models(LLMs) have attracted increasing attention in biomedical domains due to their success in natural language processing. However, the complex traits a…
SC-TauPath: A Structural Connectivity Attribution Framework for Mapping Tau Propagation Pathways in Alzheimer's Disease
Jing Zhang, Norman Scheel, Minheng Chen +5
Understanding how structural connections are associated with tau propagation in Alzheimer's disease (AD) remains a central open question, yet existing computational models either r…
Hierarchical Semantic Tree Concept Whitening for Interpretable Image Classification
Haixing Dai, Lu Zhang, Lin Zhao +9
With the popularity of deep neural networks (DNNs), model interpretability is becoming a critical concern. Many approaches have been developed to tackle the problem through post-ho…
Using Structural Similarity and Kolmogorov-Arnold Networks for Anatomical Embedding of Cortical Folding Patterns
Minheng Chen, Chao Cao, Tong Chen +7
The 3-hinge gyrus (3HG) is a newly defined folding pattern, which is the conjunction of gyri coming from three directions in cortical folding. Many studies demonstrated that 3HGs c…
AD-GPT: Large Language Models in Alzheimer's Disease
Ziyu Liu, Lintao Tang, Zeliang Sun +11
Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer'…
Representative Functional Connectivity Learning for Multiple Clinical groups in Alzheimer's Disease
Lu Zhang, Xiaowei Yu, Yanjun Lyu +2
Mild cognitive impairment (MCI) is a high-risk dementia condition which progresses to probable Alzheimer's disease (AD) at approximately 10% to 15% per year. Characterization of gr…