papers
Publications (3)
q-bio.GN2016
Cytomegalovirus Antigenic Mimicry of Human Alloreactive Peptides: A Potential Trigger for Graft versus Host Disease
Charles Hall, Vishal Koparde, Max Jameson-Lee +9
The association between human cytomegalovirus (hCMV) reactivation and the development of graft-versus-host-disease (GVHD) has been observed in stem cell transplantation (SCT). Seve…
q-bio.QM2014
In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation
Max Jameson-Lee, Vishal Koparde, Phil Griffith +12
Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pa…
q-bio.OT2014
Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic?
Amir A Toor, Jared D Kobulnicky, Salman Salman +14
Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical…