papers

Publications (30)

quant-ph2021

Benchmarking Quantum Chemistry Computations with Variational, Imaginary Time Evolution, and Krylov Space Solver Algorithms

Kübra Yeter-Aydeniz, Bryan T. Gard, Jacek Jakowski +5

The rapid progress of noisy intermediate-scale quantum (NISQ) computing underscores the need to test and evaluate new devices and applications. Quantum chemistry is a key applicati…

quant-ph2026

The Role of Quantum Computing in Advancing Scientific High-Performance Computing: A perspective from the ADAC Institute

Gilles Buchs, Thomas Beck, Ryan Bennink +19

Quantum computing (QC) has gained significant attention over the past two decades due to its potential for speeding up classically demanding tasks. This transition from an academic…

quant-ph2026

Exploring the use of quantum computing for facilitating spatially and temporally resolved models of a biological cell

Muralikrishnan Gopalakrishnan Meena, Dileep Kishore, Jerry M. Parks +5

The paper evaluates how quantum computing could enable multiscale whole‑cell simulations by analyzing potential speedups for atomistic, network, and spatial models and outlining al…

#whole-cell simulation#quantum algorithms#multiscale modeling#systems biology
quant-ph2025

Logical Error Rates for a [[4,2,2]]-Encoded Variational Quantum Eigensolver Ansatz

Meenambika Gowrishankar, Daniel Claudino, Jerimiah Wright +1

Quantum computing offers a potential for algorithmic speedups for applications, such as large-scale simulations in chemistry and physics. However, these speedups must yield results…

quant-ph2024

Surf-Deformer: Mitigating Dynamic Defects on Surface Code via Adaptive Deformation

Keyi Yin, Xiang Fang, Yunong Shi +3

In this paper, we introduce Surf-Deformer, a code deformation framework that seamlessly integrates adaptive defect mitigation functionality into the current surface code workflow.…

quant-ph2025

Platform Architecture for Tight Coupling of High-Performance Computing with Quantum Processors

Shane A. Caldwell, Moein Khazraee, Elena Agostini +27

We propose an architecture, called NVQLink, for connecting high-performance computing (HPC) resources to the control system of a quantum processing unit (QPU) to accelerate workloa…

quant-ph2026

LightStim: A Framework for QEC Protocol Evaluation and Prototyping with Automated DEM Construction

Xiang Fang, Ming Wang, Yue Wu +6

Fault-tolerant quantum computing increasingly demands rigorous, circuit-level evaluation of diverse quantum error correction (QEC) protocols and efficient prototyping of new ones.…

quant-ph2023

Entanglement-Based Quantum Information Technology

Zheshen Zhang, Chenglong You, Omar S. Magaña-Loaiza +7

Entanglement is a quintessential quantum mechanical phenomenon with no classical equivalent. First discussed by Einstein, Podolsky, and Rosen and formally introduced by Schrödinge…

quant-ph2024

SymBreak: Mitigating Quantum Degeneracy Issues in QLDPC Code Decoders by Breaking Symmetry

Keyi Yin, Xiang Fang, Jixuan Ruan +7

Quantum error correction (QEC) is critical for scalable and reliable quantum computing, but existing solutions, such as surface codes, incur significant qubit overhead. Quantum low…

quant-ph2018

Quantum games: a review of the history, current state, and interpretation

Faisal Shah Khan, Neal Solmeyer, Radhakrishnan Balu +1

We review both theoretical and experimental developments in the area of quantum games since the inception of the subject circa 1999. We will also offer a narrative on the controver…

quant-ph2025

iSwitch: QEC on Demand via In-Situ Encoding of Bare Qubits for Ion Trap Architectures

Keyi Yin, Xiang Fang, Zhuo Chen +10

Recent advances in quantum hardware and error correction have paved the way for early fault-tolerant (EFT) quantum computing. We propose iSwitch, a hybrid system architecture for t…

quant-ph2023

Solving MaxCut with Quantum Imaginary Time Evolution

Rizwanul Alam, George Siopsis, Rebekah Herrman +3

We introduce a method to solve the MaxCut problem efficiently based on quantum imaginary time evolution (QITE). We employ a linear Ansatz for unitary updates and an initial state i…

quant-ph2024

QECC-Synth: A Layout Synthesizer for Quantum Error Correction Codes on Sparse Hardware Architectures

Keyi Yin, Hezi Zhang, Xiang Fang +4

Quantum Error Correction (QEC) codes are essential for achieving fault-tolerant quantum computing (FTQC). However, their implementation faces significant challenges due to disparit…

quant-ph2026

Benchmarking quantum simulation with neutron-scattering experiments

Yi-Ting Lee, Keerthi Kumaran, Bibek Pokharel +7

Realistic simulation of quantum materials is a central goal of quantum computation. Although quantum processors have advanced rapidly in scale and fidelity, it has remained unclear…

quant-ph2025

QuSplit: Achieving Both High Fidelity and Throughput via Job Splitting on Noisy Quantum Computers

Jinyang Li, Yuhong Song, Yipei Liu +4

With the progression into the quantum utility era, computing is shifting toward quantum-centric architectures, where multiple quantum processors collaborate with classical computin…

quant-ph2021

Benchmarking Embedded Chain Breaking in Quantum Annealing

Erica Grant, Travis Humble

Quantum annealing solves combinatorial optimization problems by finding the energetic ground states of an embedded Hamiltonian. However, quantum annealing dynamics under the embedd…

quant-ph2023

Toward Consistent High-fidelity Quantum Learning on Unstable Devices via Efficient In-situ Calibration

Zhirui Hu, Robert Wolle, Mingzhen Tian +3

In the near-term noisy intermediate-scale quantum (NISQ) era, high noise will significantly reduce the fidelity of quantum computing. Besides, the noise on quantum devices is not s…

quant-ph2026

Bridging Superconducting and Neutral-Atom Platforms for Efficient Fault-Tolerant Quantum Architectures

Xiang Fang, Jixuan Ruan, Sharanya Prabhu +4

The transition to the fault-tolerant era exposes the limitations of homogeneous quantum systems, where no single qubit modality simultaneously offers optimal operation speed, conne…

quant-ph2024

TANQ-Sim: Tensorcore Accelerated Noisy Quantum System Simulation via QIR on Perlmutter HPC

Ang Li, Chenxu Liu, Samuel Stein +7

Although there have been remarkable advances in quantum computing (QC), it remains crucial to simulate quantum programs using classical large-scale parallel computing systems to va…

quant-ph2023

Graph decomposition techniques for solving combinatorial optimization problems with variational quantum algorithms

Moises Ponce, Rebekah Herrman, Phillip C. Lotshaw +4

The quantum approximate optimization algorithm (QAOA) has the potential to approximately solve complex combinatorial optimization problems in polynomial time. However, current nois…

quant-ph2019

Continuous-Time Quantum Walks on Dynamic Graphs

Rebekah Herrman, Travis Humble

Continuous-time quantum walks (CTQWs) on static graphs provide efficient methods for search and sampling as well as a model for universal quantum computation. We consider an extens…

quant-ph2024

PowerMove: Optimizing Compilation for Neutral Atom Quantum Computers with Zoned Architecture

Jixuan Ruan, Xiang Fang, Hezi Zhang +3

Neutral atom-based quantum computers (NAQCs) have recently emerged as promising candidates for scalable quantum computing, largely due to their advanced hardware capabilities, part…

quant-ph2018

Hybrid Programming for Near-term Quantum Computing Systems

Alexander McCaskey, Eugene Dumitrescu, Dmitry Liakh +1

Recent computations involving quantum processing units (QPUs) have demonstrated a series of challenges inherent to hybrid classical-quantum programming, compilation, execution, and…

quant-ph2019

Quantum Computing based Hybrid Solution Strategies for Large-scale Discrete-Continuous Optimization Problems

Akshay Ajagekar, Travis Humble, Fengqi You

Quantum computing (QC) has gained popularity due to its unique capabilities that are quite different from that of classical computers in terms of speed and methods of operations. T…

quant-ph2020

Benchmarking Quantum Annealing Controls with Portfolio Optimization

Erica Grant, Travis Humble, Benjamin Stump

Quantum annealing offers a novel approach to finding the optimal solutions for a variety of computational problems, where the quantum annealing controls influence the observed perf…

quant-ph2025

Computational Performance Bounds Prediction in Quantum Computing with Unstable Noise

Jinyang Li, Samudra Dasgupta, Yuhong Song +3

Quantum computing has significantly advanced in recent years, boasting devices with hundreds of quantum bits (qubits), hinting at its potential quantum advantage over classical com…

quant-ph2026

Quantum-HPC Software Stacks and the openQSE Reference Architecture: A Survey

Amir Shehata, Brian Austin, Tom Beck +22

Quantum resources are increasingly integrated into high-performance computing (HPC) and cloud environments, but quantum high-performance computing (QHPC) software stacks remain iso…

quant-ph2025

TrapSIMD: SIMD-Aware Compiler Optimization for 2D Trapped-Ion Quantum Machines

Jixuan Ruan, Hezi Zhang, Xiang Fang +8

Modular trapped-ion (TI) architectures offer a scalable quantum computing (QC) platform, with native transport behaviors that closely resemble the Single Instruction Multiple Data…

quant-ph2024

CaliScalpel: In-Situ and Fine-Grained Qubit Calibration Integrated with Surface Code Quantum Error Correction

Xiang Fang, Keyi Yin, Yuchen Zhu +8

Quantum Error Correction (QEC) is a cornerstone of fault-tolerant, large-scale quantum computing. However, qubit error drift significantly degrades QEC performance over time, neces…

cs.LG2024

Adiabatic Quantum Support Vector Machines

Prasanna Date, Dong Jun Woun, Kathleen Hamilton +7

Adiabatic quantum computers can solve difficult optimization problems (e.g., the quadratic unconstrained binary optimization problem), and they seem well suited to train machine le…