Publications (5)
3D RNA and functional interactions from evolutionary couplings
Caleb Weinreb, Adam J. Riesselman, John B. Ingraham +3
Non-coding RNAs are ubiquitous, but the discovery of new RNA gene sequences far outpaces research on their structure and functional interactions. We mine the evolutionary sequence…
Sorting sums of binary decision summands
Torsten Gross, Nils Blüthgen
A sum where each of the summands can be independently chosen from two choices yields possible summation outcomes. There is an -algorithm that finds the…
RECOVER: sequential model optimization platform for combination drug repurposing identifies novel synergistic compounds in vitro
Paul Bertin, Jarrid Rector-Brooks, Deepak Sharma +17
For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dos…
Modulational instability and resonant wave modes act on the metastability of oscillator chains
Torsten Gross, Dirk Hennig, Lutz Schimansky-Geier
We describe the emergence and interactions of breather modes and resonant wave modes within a two-dimensional ring-like oscillator chain in a microcanonical situation. Our analytic…
Self-organized escape processes of linear chains in nonlinear potentials
Torsten Gross, Dirk Hennig, Lutz Schimansky-Geier
An enhancement of localized nonlinear modes in coupled systems gives rise to a novel type of escape process. We study a spatially one dimensional set-up consisting of a linearly co…