Publications (5)
Solving the Tyranny of Pipetting
Stephen Quake
Stephen Quake is the Lee Otterson Professor of Bioengineering and Applied Physics at Stanford University. Here he reviews the early history of microfluidics and discusses more rece…
The Environment-Dependent Regulatory Landscape of the E. coli Genome
Tom Röschinger, Heun Jin Lee, Rosalind Wenshan Pan +7
All cells respond to changes in both their internal milieu and the environment around them through the regulation of their genes. Despite decades of effort, there remain huge gaps…
Designing the statistically optimal drug for cancer therapy
Patrick N. Lawlor, Tomer Kalisky, Stephen Quake +3
Cancer and healthy cells have distinct distributions of molecular properties and thus respond differently to drugs. Cancer drugs ideally kill cancer cells while limiting harm to he…
Corvo: Visualizing CellxGene Single-Cell Datasets in Virtual Reality
Luke Hyman, Ivo F. Sbalzarini, Stephen Quake +1
The CellxGene project has enabled access to single-cell data in the scientific community, providing tools for browsed-based no-code analysis of more than 500 annotated datasets. Ho…
Informational blueprints reveal condition-dependent gene regulatory architectures
Doruk Efe Gökmen, Rosalind Wenshan Pan, Tom Röschinger +4
While coding regions in the genome have a direct interpretation in terms of protein products, significant fractions are non-coding and yet control essential biological functions. U…