Publications (9)
Conflation of short identity-by-descent segments bias their inferred length distribution
Charleston W. K. Chiang, Peter Ralph, John Novembre
Identity-by-descent (IBD) is a fundamental concept in genetics with many applications. In a common definition, two haplotypes are said to contain an IBD segment if they share a seg…
Bi-Encoders based Species Normalization -- Pairwise Sentence Learning to Rank
Zainab Awan, Tim Kahlke, Peter Ralph +1
Motivation: Biomedical named-entity normalization involves connecting biomedical entities with distinct database identifiers in order to facilitate data integration across various…
Population-scale Ancestral Recombination Graphs with tskit 1.0
Ben Jeffery, Yan Wong, Kevin Thornton +49
Ancestral recombination graphs (ARGs) are an increasingly important component of population and statistical genetics. The tskit library has become key infrastructure for the field,…
Parallel adaptation: One or many waves of advance of an advantageous allele?
Peter Ralph, Graham Coop
Our models for detecting the effect of adaptation on population genomic diversity are often predicated on a single newly arisen mutation sweeping rapidly to fixation. However, a po…
Disentangling the effects of geographic and ecological isolation on genetic differentiation
Gideon Bradburd, Peter Ralph, Graham Coop
Populations can be genetically isolated both by geographic distance and by differences in their ecology or environment that decrease the rate of successful migration. Empirical stu…
Brownian motion on disconnected sets, basic hypergeometric functions, and some continued fractions of Ramanujan
Shankar Bhamidi, Steven N. Evans, Ron Peled +1
Motivated by Lévy's characterization of Brownian motion on the line, we propose an analogue of Brownian motion that has as its state space an arbitrary closed subset of the line t…