papers

Publications (36)

cs.CL2024

What's the Magic Word? A Control Theory of LLM Prompting

Aman Bhargava, Cameron Witkowski, Shi-Zhuo Looi +1

Prompt engineering is crucial for deploying LLMs but is poorly understood mathematically. We formalize LLM systems as a class of discrete stochastic dynamical systems to explore pr…

cond-mat.soft2025

Geometry-Dependent Defect Merging Induces Bifurcated Dynamics in Active Networks

Fan Yang, Shichen Liu, Hao Wang +3

Cytoskeletal networks can repair defects to maintain structural integrity. However, the mechanisms and dynamics of defect merging remain poorly understood. Here we report a geometr…

cs.AI2025

Economic Evaluation of LLMs

Michael J. Zellinger, Matt Thomson

Practitioners often navigate LLM performance trade-offs by plotting Pareto frontiers of optimal accuracy-cost trade-offs. However, this approach offers no way to compare between LL…

q-bio.CB2021

Signaling receptor localization maximizes cellular information acquisition in spatially-structured, natural environments

Zitong Jerry Wang, Matt Thomson

Cells in natural environments like tissue or soil sense and respond to extracellular ligands with intricately structured and non-monotonic spatial distributions that are sculpted b…

cond-mat.soft2025

Boundaries Program Deformation in Isolated Active Networks

Zixiang Lin, Shichen Liu, Shahriar Shadkhoo +9

Cellular structures must organize themselves within strict physical constraints, operating with finite resources and well-defined boundaries. Classical systems demonstrate only pas…

physics.bio-ph2024

Motor-driven microtubule diffusion in a photobleached dynamical coordinate system

Soichi Hirokawa, Heun Jin Lee, Rachel A Banks +4

Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering p…