papers

Publications (21)

q-bio.GN2024

Probing omics data via harmonic persistent homology

Davide Gurnari, Aldo Guzmán-Sáenz, Filippo Utro +3

Identifying molecular signatures from complex disease patients with underlying symptomatic similarities is a significant challenge in the analysis of high dimensional multi-omics d…

quant-ph2023

Quantum Analog of Shannon's Lower Bound Theorem

Saugata Basu, Laxmi Parida

Shannon proved that almost all Boolean functions require a circuit of size . We prove a quantum analog of this classical result. Unlike in the classical case the number…

quant-ph2024

Towards quantum computing for clinical trial design and optimization: A perspective on new opportunities and challenges

Hakan Doga, M. Emre Sahin, Joao Bettencourt-Silva +10

Clinical trials are pivotal in the drug discovery process to determine the safety and efficacy of a drug candidate. The high failure rates of these trials are attributed to deficie…

quant-ph2026

Experimental implementation of a discrete-time quantum walk on biological networks

Viacheslav Dubovitskii, Filippo Utro, Aritra Bose +3

Quantum walks provide a versatile framework for probing the structural and dynamical properties of complex systems ranging from biological networks to synthetic materials. However,…

math.CO2026

Bounds on the realizations of zero-nonzero patterns and sign conditions of polynomials restricted to varieties and applications

Saugata Basu, Laxmi Parida

We obtain upper bounds, independent of the ambient dimension, for the number of realizable zero-nonzero patterns and (over ordered fields) sign conditions of a finite family of pol…

math.AT2026

Essential Simplices Dominate in Harmonic Representatives of One-Dimensional Persistent Classes

Saugata Basu, Aldo Guzmán-Sáenz, Laxmi Parida

The paper proves that for generic one‑dimensional persistent homology classes, harmonic cycle representatives give strictly larger (in absolute value) coefficients to essential edg…

#persistent homology#harmonic cycles#essential simplices#one-dimensional bars