papers

Publications (5)

cs.DC2021

Pandemic Drugs at Pandemic Speed: Infrastructure for Accelerating COVID-19 Drug Discovery with Hybrid Machine Learning- and Physics-based Simulations on High Performance Computers

Agastya P. Bhati, Shunzhou Wan, Dario Alfè +26

The race to meet the challenges of the global pandemic has served as a reminder that the existing drug discovery process is expensive, inefficient and slow. There is a major bottle…

physics.comp-ph2020

Integrating State of the Art Compute, Communication, and Autotuning Strategies to Multiply the Performance of the Application Programm CPMD for Ab Initio Molecular Dynamics Simulations

Tobias Klöffel, Gerald Mathias, Bernd Meyer

We present our recent code modernizations of the of the ab initio molecular dynamics program CPMD (www.cpmd.org) with a special focus on the ultra-soft pseudopotential (USPP) code…

cs.DC2016

Extreme Scale-out SuperMUC Phase 2 - lessons learned

Nicolay Hammer, Ferdinand Jamitzky, Helmut Satzger +36

In spring 2015, the Leibniz Supercomputing Centre (Leibniz-Rechenzentrum, LRZ), installed their new Peta-Scale System SuperMUC Phase2. Selected users were invited for a 28 day extr…

cs.DC2026

Node-Level Performance and Energy Characterization of Flagship Science Applications on SuperMUC-NG Phase 2

Salvatore Cielo, Elmira Birang, Alexander Pöppl +5

We present a systematic performance and energy-efficiency characterization of five flagship scientific workloads on SuperMUC-NG phase 2, the 28 PetaFLOPs system at the Leibniz Supe…

cs.DC2020

IMPECCABLE: Integrated Modeling PipelinE for COVID Cure by Assessing Better LEads

Aymen Al Saadi, Dario Alfe, Yadu Babuji +33

The drug discovery process currently employed in the pharmaceutical industry typically requires about 10 years and $2-3 billion to deliver one new drug. This is both too expensive…