Publications (6)
Efficiency Requires Adaptation
Adam Lane
The majority of historical designs are a priori in nature, where a priori indicates a design can be specified in advance of the experiment. The conventional wisdom is that the set…
Efficiency of Observed Information Adaptive Designs
Adam Lane
In this work the primary objective is to maximize the precision of the maximum likelihood estimate in a linear regression model through the efficient design of the experiment. One…
Adaptive Designs for Optimal Observed Fisher Information
Adam Lane
Expected Fisher information can be found a priori and as a result its inverse is the primary variance approximation used in the design of experiments. This is in contrast to the co…
Optimal Relevant Subset Designs in Nonlinear Models
Adam Lane
Fisher (1934) argued that certain ancillary statistics form a relevant subset, a subset of the sample space on which inference should be restricted, and showed that conditioning on…
On the Evidence for Violation of the Equivalence Principle in Disk Galaxies
Corey Sargent, William Clark, Antonia Seifert +5
We examine the claimed observations of a gravitational external field effect (EFE) reported in Chae et al. We show that observations suggestive of the EFE can be interpreted withou…
Conditional Information and Inference in Response-Adaptive Allocation Designs
Adam Lane
Response-adaptive allocation designs refer to a class of designs where the probability an observation is assigned to a treatment is changed throughout an experiment based on the ac…